The Nike Run Defy and On Cloudflow 4 Distance are both neutral road running shoes. The Run Defy costs about $60 less (from $49.97).
Specs side by side
| Spec | Run Defy | Cloudflow 4 Distance |
|---|---|---|
| Price | $49.97 | $110–$160 |
| Rating | 4.7 / 5 (240 reviews) | — |
| Weight | 8.2 oz | 8.3 oz |
| Heel-to-toe drop | 10 mm | 9 mm |
| Cushioning | — | Firm / responsive |
| Support | Neutral | Neutral |
| Surface | Road | Road |
| Available for | Men & Women | Men & Women |
Specs and prices from Nike and On, checked 2026-10-11. Weight is usually for a men's size 9–10.
Which should you get?
Get the Run Defy if…
- you want to spend less
Get the Cloudflow 4 Distance if…
- it fits you better or you like its colors

