The Adidas Adizero SL2 and Nike Run Defy are both neutral road running shoes. The Adizero SL2 is 0.9 oz lighter (7.3 oz vs 8.2 oz).
Specs side by side
| Spec | Adizero SL2 | Run Defy |
|---|---|---|
| Price | $52 | $49.97–$65 |
| Rating | 4.7 / 5 (482 reviews) | 4.7 / 5 (240 reviews) |
| Weight | 7.3 oz | 8.2 oz |
| Heel-to-toe drop | 9 mm | 10 mm |
| Heel stack height | 35 mm | — |
| Cushioning | Moderate | — |
| Support | Neutral | Neutral |
| Surface | Road | Road |
| Available for | Women | Men & Women |
Specs and prices from Adidas and Nike, checked 2026-11-02. Weight is usually for a men's size 9–10.
Which should you get?
Get the Adizero SL2 if…
- you want the lighter shoe
- you want the more widely reviewed shoe
Get the Run Defy if…
- it fits you better or you like its colors