The Nike Interact Run and Saucony Endorphin Pro 5 are both neutral road running shoes. The Interact Run costs about $155 less (from $85). The Endorphin Pro 5 has a lower heel-to-toe drop (8 mm vs 10 mm).
Bottom line: Pick the Interact Run if you want to spend less; pick the Endorphin Pro 5 if you land on your midfoot or want a lower drop.
Specs side by side
| Spec | Interact Run | Endorphin Pro 5 |
|---|---|---|
| Price | $85 | $240 |
| Rating | — | 3.7 / 5 (259 reviews) |
| Weight | 7.4 oz | 7.3 oz |
| Heel-to-toe drop | 10 mm | 8 mm |
| Heel stack height | — | 39.5 mm |
| Cushioning | — | Moderate |
| Support | Neutral | Neutral |
| Plate | None | Carbon |
| Surface | Road | Road |
| Available for | Women | Men & Women |
Specs and prices from Nike and Saucony, checked 2026-11-02. Weight is usually for a men's size 9–10.
Which should you get?
Get the Interact Run if…
- you want to spend less
- you land on your heel and like a higher drop
Get the Endorphin Pro 5 if…
- you land on your midfoot or want a lower drop
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